France's far-right National Front (FN) has failed to win a single region in the second round of elections, exit polls indicate.
Early results suggest the party was beaten into third place, despite leading in six of 13 regions in the first round of votes a week ago.
The polls predict Nicolas Sarkozy's centre-right Republicans will win most seats ahead of the ruling Socialists.
Acknowledging defeat, Ms Le Pen pledged to keep fighting.
"Nothing can stop us. Long live the French Republic! Long live the nation! Long live France!" she told her supporters.
Early results suggest the party was beaten into third place, despite leading in six of 13 regions in the first round of votes a week ago.
The polls predict Nicolas Sarkozy's centre-right Republicans will win most seats ahead of the ruling Socialists.
Acknowledging defeat, Ms Le Pen pledged to keep fighting.
"Nothing can stop us. Long live the French Republic! Long live the nation! Long live France!" she told her supporters.