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Hydroxychloroquine, chloroquine and macrolides for Covid-19



Harry Wilson's tackle

Harry Wilson's tackle

Harry Wilson's Tackle
NSC Patron
Oct 8, 2003
49,869
Faversham
Fail to work, increase death rate and cause cardiac arrhythmias."We were unable to confirm a benefit of hydroxychloroquine or chloroquine, when used alone or with a macrolide, on in-hospital outcomes for COVID-19. Each of these drug regimens was associated with decreased in-hospital survival and an increased frequency of ventricular arrhythmias when used for treatment of COVID-19."

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)31180-6/fulltext
 




The Wizard

The Wizard

Well-known member
Jul 2, 2009
18,383
It’s very strange how the same drug seems to be causing such diversion of opinions between scientists, seen a fair few studies saying it gives an increased recovery rate then others saying it’s actually worse for the patient to take this. So many questions and so few answers as of yet.
 


D

darkwolf666

Well-known member
Nov 8, 2015
7,576
Sittingbourne, Kent
The Wizard said:
It’s very strange how the same drug seems to be causing such diversion of opinions between scientists, seen a fair few studies saying it gives an increased recovery rate then others saying it’s actually worse for the patient to take this. So many questions and so few answers as of yet.
Click to expand...

Ask Donald, he knows all the answers, he is positive that it's a positive drug and not negative, unless it's a result of a test, then it's a positive negative - I think!
 


Harry Wilson's tackle

Harry Wilson's tackle

Harry Wilson's Tackle
NSC Patron
Oct 8, 2003
49,869
Faversham
The Wizard said:
It’s very strange how the same drug seems to be causing such diversion of opinions between scientists, seen a fair few studies saying it gives an increased recovery rate then others saying it’s actually worse for the patient to take this. So many questions and so few answers as of yet.
Click to expand...

It is standard for individual studies to show apparent benefit; only when there have been several is the picture clear. The standard method of evaluating the truth of the matter is a meta analysis where successive published trials are bundled together. The Lancet paper is a different type of assessment but it is massive, and much more credible than individual trials. I am definitely persuaded there is no benefit against Covid, and a small increased risk of an adverse outcome.
 


Harry Wilson's tackle

Harry Wilson's tackle

Harry Wilson's Tackle
NSC Patron
Oct 8, 2003
49,869
Faversham
A mate who works for one of the big pharma companies sent me this today:

Drugs being examined for possible Covid 19 application:

Lopinavir/ Ritonavir
Remdesivir
Chloroquine (or hydroxychloroquine)
Duvelisib
Favipiravir
Tocilizumab
Isotretinoin
Losartan
Plitidepsin
Canakinumab
Ruxolitinib
Baricitinib
Ivermectin
Atorvastatin
Acalabrutinib
Chlorpromazine
Leflunomide
Dapagliflozin
Sarilumab
Amiodarone or Verapamil
Ramipril
Sirolimus
Imatinib
Lenalidomide
Ulinastatin
Clazakizumab

**** me. There is money to be made and some fuggers will be making it :facepalm:
 




Weststander

Weststander

Well-known member
NSC Patron
Aug 25, 2011
63,881
Withdean area
Harry Wilson's tackle said:
A mate who works for one of the big pharma companies sent me this today:

Drugs being examined for possible Covid 19 application:

Lopinavir/ Ritonavir
Remdesivir
Chloroquine (or hydroxychloroquine)
Duvelisib
Favipiravir
Tocilizumab
Isotretinoin
Losartan
Plitidepsin
Canakinumab
Ruxolitinib
Baricitinib
Ivermectin
Atorvastatin
Acalabrutinib
Chlorpromazine
Leflunomide
Dapagliflozin
Sarilumab
Amiodarone or Verapamil
Ramipril
Sirolimus
Imatinib
Lenalidomide
Ulinastatin
Clazakizumab

**** me. There is money to be made and some fuggers will be making it :facepalm:
Click to expand...

In a White House game of Pin The Tail On The Donkey on 19th March, from that long list Donald pinned the third.

The rest is history.
 


beorhthelm

beorhthelm

A. Virgo, Football Genius
Jul 21, 2003
35,290
Weststander said:
In a White House game of Pin The Tail On The Donkey on 19th March, from that long list Donald pinned the third.

The rest is history.
Click to expand...

to be fair it wasnt random, the Chinese where trying chloroquine as a therapy back in February. iroinc eh?
 


Herr Tubthumper

Herr Tubthumper

Well-known member
NSC Patron
Jul 11, 2003
59,467
The Fatherland
Harry Wilson's tackle said:
A mate who works for one of the big pharma companies sent me this today:

Drugs being examined for possible Covid 19 application:

Lopinavir/ Ritonavir
Remdesivir
Chloroquine (or hydroxychloroquine)
Duvelisib
Favipiravir
Tocilizumab
Isotretinoin
Losartan
Plitidepsin
Canakinumab
Ruxolitinib
Baricitinib
Ivermectin
Atorvastatin
Acalabrutinib
Chlorpromazine
Leflunomide
Dapagliflozin
Sarilumab
Amiodarone or Verapamil
Ramipril
Sirolimus
Imatinib
Lenalidomide
Ulinastatin
Clazakizumab

**** me. There is money to be made and some fuggers will be making it :facepalm:
Click to expand...

There will also be combinations tested as well. I was at a presentation yesterday which said pretty much every drug which might have an impact on treatment is being tested.
 


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