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This would be your best option and most likely to be running on the strike day however do allow some time for delays

Don’t do rail Europe. Your safest bet would be Milan Central return to Rome with ‘Italo’ From Milan Train station allow your self time to get to the airport by bus/taxi. Also in Rome Italo doesn’t always stop in Termini and has 2 other stops in the center Roma Tiburtina and Roma Ostiense

There is very little interest here at the moment but if anything changes I’ll make a new thread or stick it on top of this one.

@Hotchilidog - Italo Trains are the high speed(private) trains. Even when there is nationwide strikes most of their high speed trains still usually go ahead.

In Italy it’s possible. Atleast 1/2 every month! The strike is on March 8th and nearly always nationwide strikes are on Friday here. Regional strikes vary.