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Very handy to know this. It sounds very similar to the effect of the build up and execution of every corner of ours last season, even for those not taking Bisoprolol....:)

It's on the list of things not to take with Apixaban (without doctor's approval and when asked they said that any NSAIDs such as Iboprofen are a no no because they increase the risk of bleeding.)

Yes sounds sensible, especially with your added risk of thin skin! Yes it was the thinners where I was worried about bleeding.

Thanks! That's what I was hoping - I will go for the 6am thing too I think!

Thanks @FamilyGuy - all these other cases like yours makes me realise that many others facing much worse and more worrying, so probably need to get a grip on worries over meds! Glad to hear that things have stabilised. With all your woodwork do you worry about cuts / bleeding etc as that is one...

Thanks for all that info @Harry Wilson's tackle (with endorsement from @lawros left foot ) - I will PM you! These symptoms all very familiar (suddenly). It's taken a while to get attention from the cardiologist out of appointment sequence via GP etc but they seemed so concerned about the...

Thanks - does that mean piss a lot all day or just for a couple of hours after taking (thinking about manageability of this at work etc)?

Thanks @Lifelong Supporter and @Algernon - that's very kind of you to share all that info. And generally reassuring. Glad to hear side effects sound reasonably tolerable alongside the benefits the meds bring. It also makes one feel quite fortunate reading of your quite scary experiences - and...

I've seen various AF mentions along the way but couldn't find a thread like this but I'm aware that others on NSC have experienced AF and similar problems. I am of course asking here 'on behalf of a good friend'......'they' are 70 and have had a floppy / leaky mitral valve for at least 15 years...