Because if Andone was to our for a month and Murray pulls a hamstring tomorrow we would be seriously jeopardising our premier league future. For me it’s just not worth the risk.
If Andone is going to be out for a while then wrap Murray in cotton wool and start Locadia. The risk of having neither Murray nor Andone is simply to big. Also don't risk Gross if not fully fit.
Other than that start with a full strength side and hopefully give Izquierdo some good game time.