I think social distancing really hampers the studio bits as you don't get the immediate audience reaction to stuff in the same way. Half of the joy of (e.g.) the Joe Wilkinson potato throw was the instant crowd reaction. The filmed stuff is as good as ever IMHO. And the Wozniak moment was...
Richard Ayoade
David Mitchell
Victoria Coren Mitchell
Sue Perkins
Alex Brooker
The Mitchells as the two person team because it would genuinely be fascinating watching a married couple do it