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Can I ask about your peripheral neuropathy, please? It’s a known, albeit somewhat unusual, side effect of allopurinol. Over the last 4-6 months I’ve developed a much milder form of neuropathy than that which you describe - but it’s getting worse. What dose of allopurinol were you on? When you...

I imagine you can get it in the thumb, but it’s extremely unlikely to develop where you describe. It occurs in joints...and there none where you describe.

Yes. I use it once a month for uric acid (while I'm doing it I test for glucose and cholesterol every six months using the same kit). I find that the uric acid levels rise above the danger level (which for me is 340-350) about a week in advance of an impending attack. If I see the acid level...