Infliximab proved to be a wonder-drug for Mrs Airman for a good couple of years, in 17 years of marriage I think that was the wellest I've known her for such an extended period. Very expensive though (for the NHS).
I've every sympathy for you all. My wife has had Crohn's for some 20 years now and she's been through the ringer with all manner of drugs and the inevitable re-sections. Nearly came a cropper once when her GP wouldn't listen to her (She knew she was blocked, but he thought he knew better), but...