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I've just caught up with this thread and on reading some of the posts, the above in particular, I need to be thankful that nothing like this has happened to me. I got diagnosed almost 29 years ago not long after my 17th birthday. Bizarrely I first started having symptoms on the day of the trip...

I suffer from Crohn's Disease. Thankfully it's pretty well controlled these days. I think it probably does tire me out quite a lot.