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It's hard isn't it? These things are. What I will say is that the trans people I know well have known since very early childhood and have tried to live straight, then gay before finally addressing it. Despite the widespread discrimination (because as this thread and recent press demonstrate it...

Or make an effort to talk to trans people about their experiences and see if there is anything we can learn individually and collectively. Far easier to just stay scared though, I guess.

Woo-hoo! A load of cis, straight, white guys sharing their thoughts on something they know absolutely **** all about. It's what this forum does best.

Biology you say? https://en.wikipedia.org/wiki/Intersex