Scientists at Imperial College London induced intense psychedelic trips in 12 people using high doses of the banned substance psilocybin.
A week after the experience all the volunteers were depression-free, and three months later five still had no symptoms of the condition...
https://www.theguardian.com/society/2017/may/23/study-hallucinogenic-mushrooms-safest-recreational-drug-lsd
Of the more than 12,000 people who reported taking psilocybin hallucinogenic mushrooms in 2016, just 0.2% of them said they needed emergency medical treatment – a rate at least five times...