We've got quite a few in our office (Canary Wharf) that commute from places like Birmingham, Southampton and North/East of Cambridge, 2-2.5 hours not uncommon. Home working is becoming more and more prevalent now though - only a matter of time before we start to get larger numbers of people...
Loads I know.............would have binned it myself if I had to commute daily. As it is, working from home 2-3 days a week and travelling at least one week a month makes it bearable.