Probably also worth noting is that although the official speed limit on Dutch motorways is 130km/h (except some clearly marked areas that are 120 or 100), there is (in a bid to reduce emissions) a blanket limit of 100km/h that applies nationwide from 6am to 7pm. After 7pm you can put your foot...
As has been mentioned above, it's a good idea to avoid hitting the Antwerp ring road at peak times.
A lesser-known pinch point if you're driving via the A27 between Breda and Utrecht is a bridge around the town of Gorinchem. I wake up every morning to Dutch news radio and that area features...