With one source it depends how your sending the signal - if it's over speaker wired from a power amp then there are obstacles, but if it's a digital source and you have a DAC and Amp in each room, it should be fine.
I'd start with what you want to be able to do from a convenience (or tactile...
If it's just something to look fancy, B&O could work, but given that you're asking the question, I guess that's not what you're after.
So what are you after (amp, speakers, audio around the house etc)?